| Date | Opponent | Score | Location | Details | |
1921 | |||||
| Fri, Sep 30 | Boston | W | 48-0 | H | ['more'] |
| Fri, Oct 7 | Bainbridge | L | 0-28 | A | ['more'] |
| Fri, Oct 14 | Albany | L | 0-27 | A | ['more'] |
| Sat, Oct 22 | Leon, FL | T | 7-7 | H | ['more'] |
| Sat, Oct 29 | Leon, FL | L | 0-27 | A | ['more'] |
| Fri, Nov 4 | Bainbridge | L | 0-27 | H | ['more'] |
| Fri, Nov 11 | Quitman | W | 19-0 | A | ['more'] |
| Fri, Nov 18 | Valdosta | L | 0-35 | H | ['more'] |
| Thu, Nov 24 | Quitman | W | 27-0 | H | ['more'] |
| Totals for 1921 | 3-5-1 | ||||